Allison Janney

Sue Buttons

Mila Kunis

Nancy

Regina Hall

Cam Harris

Awkwafina

Mina

Wanda Sykes

Rita

Ellen Barkin

Debbie

Matthew Modine

Karl Buttons

Jimmi Simpson

Petey Buttons

Keong Sim

Mr. Kim

Juliette Lewis

Gloria Michaels

Clifton Collins Jr.

Ray

Samira Wiley

Jonelle

Bridget Everett

Leah Norton

T.C. Matherne

Officer Jones

Dominic Burgess

Captain Riggins

Chris Lowell

Steve

Michael A. Newcomer

Jonathan Rose

Liz Elkins Newcomer

Robin Rose

Shannon Cogan

Kentucky News Anchor

Cleta Elaine Ellington

Bakery Clerk

Susan McPhail

Sweet Elderly Motel Clerk

Lucy Faust

Janet

CC Castillo

Roberta

Zack Shires

Teenage Boy

Nathan Wells

Kentucky News Anchor #1

Cherita Brent

Kentucky News Anchor #2

Sampley Barinaga

Teen Asshole

Connor Hammond

Drugged Out Teen

K. Steele

Officer #1

Jock McKissic

Lennie

Joseph Landry

Camera Man

Peter Jaymes Jr.

Tech Guy

Sylvia Grace Crim

Make-Up Woman

Emily Russell

Gloria's Assistant

Deneen Tyler

Bank Manager

Alex Stage

Lab Tech

Ryan Baughman

Employee

Reggi Marion

News Reporter

Virginia Patterson

Granny Rose

Rukey Styles

Pissed Off Detainee

Perraniqua Champ

Employee #2

Tate Taylor

Attractive Customer

Brian Duong

Kentucky News Anchor #4

Aaron Mitchell

Stanlow Police Officer (uncredited)