Michael Douglas

Dr. Nathan Conrad

Sean Bean

Patrick Koster

Brittany Murphy

Elisabeth Burrows

Skye McCole Bartusiak

Jessie Conrad

Guy Torry

Dolen

Jennifer Esposito

Det. Sandra Cassidy

Famke Janssen

Aggie Conrad

Oliver Platt

Dr. Louis Sachs

Shawn Doyle

Russel Maddox

Victor Argo

Sydney Simon

Conrad Goode

Max Dunlevy

Paul Schulze

Jake

Lance Reddick

Arnie

Aidan Devine

Leon Edward Croft

Alex Campbell

Jonathan

Philip DeWilde

Intern

Sam Montesano

Frankie

Arlene Duncan

Aide

Judy Sinclair

Zelda Sinclair

Larry Block

Doorman

David Warshofsky

Ryan

Darren Frost

Janitor

Philip Williams

Large Cop

Louis Vanaria

Cop at Scene

Daniel Kash

Detective Garcia

Lucie Laurier

Vanessa

Isabella Fink

8-Year-Old Elisabeth

Ray Iannicelli

Man at Marina

Colm Magner

Cop #1

Cyrus Farmer

Officer #1

Martin Roach

Transit Cop

Patricia Mauceri

Sofia

Tony Bruno

Radio Host (uncredited)

Paul J.Q. Lee

Man with a Cell Phone (uncredited)

Lorli Villanueva

Chinese Woman (uncredited)