Robert De Niro

Jack Byrnes

Ben Stiller

Greg Focker

Owen Wilson

Kevin Rawley

Dustin Hoffman

Bernie Focker

Barbra Streisand

Rozalin Focker

Blythe Danner

Dina Byrnes

Teri Polo

Pam Byrnes-Focker

Jessica Alba

Andi Garcia

Laura Dern

Prudence

Kevin Hart

Nurse Louis

Daisy Tahan

Samantha Focker

Colin Baiocchi

Henry Focker

Tom McCarthy

Dr. Bob

Harvey Keitel

Randy Weir

Yul Vazquez

Junior

Jack Axelrod

Chappy

Clent Bowers

Mr. Androvsky

Olga Fonda

Svetlana

Laksh Singh

Dr. Patel

Trula M. Marcus

Stage Producer

Jake Keiffer

Rufus

Rob Huebel

Sleazy Doctor

John DiMaggio

EMT

Jordan Peele

EMT

Kelli Kirkland

EMT

Deepak Chopra

Deepak Chopra

Robbie Tucker

EHS Tough Kid

Nick Kroll

Young Doctor

Sergio Calderón

Gustavo

Aaron Zachary Philips

Confused Child

David Pressman

Doctor

Hugh Dane

Doctor

Amy Stiller

Kristen

Richard Cotovsky

Newspaper Vendor

Trinity Warren

Climbing Kid

Samuel Schultz

Climbing Kid

Cade Rogers

Climbing Kid / Bounce House Kid

Ava Rose Williams

Climbing Kid

Frankie Torres

Climbing Kid

Kyla Warren

Party Kid

Erin Haisan

Party Kid

Ryder Bucaro

Party Kid

Callder Griffith

Party Kid

Lei'lah Star

Party Kid

David Williams

Party Kid

Randy Chuang

Monk

Joe Thamawat

Monk

Harry Bali

Sadu

Paul Herman

Caricature Artist

Leslie Garavito

Fire Pit Child

Cort Rogers

Bounce House Kid

Troy Lindsay Brown

Bounce House Kid

Erika Jensen

Party Parent

Robert Miano

Party Parent

Kat Kramer

Party Parent

Roy Jones Jr.

Party Parent

Derek Ressallat

Party Parent

Vladimir Kubr

Ballpit Kid

Semere-Ab Etmet Yohannes

Fire Walker

Nicole Pano

Art Teacher

Michael Naughton

Anatomy Professor

Celina Zambón

Carmencita

Shih Chou

Party Monk

Stan Egi

Man on Subway

Juan Antonio Bolivar

Flamenco Dancer

Michelle Castillo

Flamenco Dancer

Theo Crisell

Flamenco Dancer

Neisha Folkes-LeMelle

Flamenco Dancer

Jillana Laufer

Flamenco Dancer

Molly Rogers

Flamenco Dancer

Gary Sievers

Spanish Square Patron (uncredited)

Arnold Chon

Monk (uncredited)