Philip Seymour Hoffman

Caden Cotard

Samantha Morton

Hazel

Michelle Williams

Claire Keen

Catherine Keener

Adele Lack

Emily Watson

Tammy

Dianne Wiest

Ellen Bascomb / Millicent Weems

Jennifer Jason Leigh

Maria

Hope Davis

Madeleine Gravis

Tom Noonan

Sammy Barnathan

Sadie Goldstein

Olive (4 years old)

Robin Weigert

Adult Olive

Deirdre O'Connell

Ellen's Mother

Alice Drummond

Actress Playing Frances

Amy Wright

Burning House Realtor

Elizabeth Marvel

Warehouse Realtor

Christopher Evan Welch

Pastor

Charles Techman

Like Clockwork Patient

Tom Greer

Medic

Josh Pais

Ophthalmologist

Lynn Cohen

Caden's Mother

Jerry Adler

Caden's Father

Daisy Tahan

Ariel

Frank Girardeau

Plumber

Kristen Bush

Actress Playing Claire

Stanley Krajewski

Actor as Caden

Peter Friedman

Emergency Room Doctor

Daniel London

Tom

Robert Seay

David

Stephen Adly Guirgis

Davis

Joe Lisi

Maurice

Michael Medeiros

Eric

William Ryall

Jimmy

Rosemary Murphy

Frances

John Rothman

Dentist

Paul Sparks

Derek

Tim Guinee

Needleman Actor

Michael Higgins

Actor Playing Man with Nose Bleed

Barbara Haas

Warehouse Actress

Greg McFadden

Actor Playing Needleman Actor

Alvin Epstein

Man with Nose Bleed

Gerald Emerick

Man in Line

Chris McGinn

Lady at Caden's Mom's

Dan Ziskie

Leg Tremor Doctor

Portia

Therapy Patient Actress

Nicholas Wyman

Soap Actor Doctor

Amy Spanger

Soap Actress Nurse

Timothy Doyle

Michael

Cliff Carpenter

Old Man

Raymond Angelic Sr.

German Doctor

Erica Fae

German Woman

Mark Lotito

Minister

Laura Odeh

Toystore Clerk

Deanna Storey

Jazz Singer

Frank Wood

Evaluative Services Doctor

Amanda R. Phillips

Emergency Room Nurse

Kat Peters

Ellen (10 years old)