Sandra Bullock

Ashburn

Melissa McCarthy

Mullins

Demián Bichir

Hale

Marlon Wayans

Levy

Michael Rapaport

Jason Mullins

Jane Curtin

Mrs. Mullins

Spoken Reasons

Rojas

Dan Bakkedahl

Craig

Taran Killam

Adam

Michael McDonald

Julian

Thomas F. Wilson

Captain Woods

Peter Weireter

SWAT Team Leader

John Ross Bowie

NY Agent

William Xifaras

Tough Guy #1

Cary 'Big Shug' Guy

Tough Guy #2

Erica Derrickson

Prostitute

Tony Hale

The John

Deirdre Horgan

Police Dispatch (voice)

William Ambrose Kennedy

Desk Sergeant

Tony V.

Precinct Officer

Amanda Good Hennessey

Woman with Kid

Patty Ross

Drunk Woman

Kaitlin Olson

Tatiana

Ellen Becker Gray

Tatiana's Mother

Andy Buckley

Robin

Don Orsillo

Baseball Announcer

Adam Ray

LeSoire

Chris Gethard

Chris Gethard

Dane Aska

Club Ekko Bartender

Joey McIntyre

Peter Mullins

Michael Tucci

Mr. Mullins

Bill Burr

Mark Mullins

Nate Corddry

Michael Mullins

Jessica Chaffin

Gina

Jamie Denbo

Beth

Miriam Tolan

Pathologist

Alexis Garcia

Drug Dealer in Paint Factory

Raw Leiba

Paint Factory Henchman

Ben Falcone

Blue Collar Man

Joe Stapleton

O'Flanagan's Bartender

Steve Bannos

Wayne

Fletcher McTaggart

Choking Man

Zach Woods

Paramedic

Joe Garland

Boston Agent

Thomas B. Devlin

Boston Agent

Benjamin Evett

Boston Agent

Elliot Santiago

Dealer

Mitch Silpa

Dealer

Luis Da Silva, Jr.

Dealer

Steve Grodewald

Dealer

Katie Dippold

ER Nurse

Kelby Turner Akin

Orderly

Lance Norris

Scruffy Bar Patron

Paul Feig

Doctor (uncredited)

John Franchi

Bar Patron (uncredited)

Colleen Kelly

Detective (uncredited)

Brandon Richardson

Factory Worker